1.         背景知識:
    1.       ARDS病人的BAL若GM-CSF濃度較高似乎較容易存活
    2.       GM-CSF功能
      1.       Maintains homeostasis in the lung
      2.       Maturation of alveolar macrophages 可使surfactant clearance/balance
      3.       Pulmonary innate immunity
  2.       方法: 130 patients with ARDS of at least 3 days duration and randomized them to receive either GM-CSF or placebo for 14 days
  3.      結果GM-CSF did not reduce ventilator days or 28 days mortality

文章標籤
csf gm days ards macrophages alveolar surfactant innate maturation ventilator

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