- 背景知識:
- ARDS病人的BAL若GM-CSF濃度較高似乎較容易存活
- GM-CSF功能
- Maintains homeostasis in the lung
- Maturation of alveolar macrophages 可使surfactant clearance/balance
- Pulmonary innate immunity
- 方法: 130 patients with ARDS of at least 3 days duration and randomized them to receive either GM-CSF or placebo for 14 days
- 結果GM-CSF did not reduce ventilator days or 28 days mortality
- Jul 19 Thu 2012 14:12
GM-CSF for acute lung injury & ARDS (RCT, Crit Care Med)